Clinical analysis of mental and behavioral disorders in elderly

Upload time:2017-02-23 Browse:

Author: Guo Yane Guo Yanjun Wang Shuhui is Yanchang * * Zhou Bo in the Jia Jianjun Wang Zhenfu Wu Weiping
Abstract: Objective To study the incidence and severity of mental and behavioral symptoms in elderly people with cognitive impairment. Methods a cross-sectional study was conducted using the neuropsychiatric inventory sources (neuropsychiatric Inventory-Questionnaire, version NPI-Q) scale of the author and hospital memory clinic were older than 80 years with memory complaints in elderly people were investigated, compared the incidence and severity of cognitive function in normal subjects and patients with dementia between mental and behavioral symptoms the. Results a total of 535 patients were included in this study, of which, the cognitive function was normal in the group of 159 and the dementia in the other group (n = 376). The results of NPI-Q showed that in the past 1 months, up to 86.7% of dementia patients had at least one mental and behavioral symptoms, while the control group was significantly lower than that in the dementia group (P<0.01), with an incidence rate of 72.3%. In the dementia group, apathy / indifferent (59.8%), nocturnal behavior and sleep disorders (47.3%) and irritability / emotional instability (46.8%) is the 3 most common and most serious, the apathy / indifferent and irritability / emotional instability symptoms were significantly higher than that of normal cognitive function group (P<0.01). The total score of NPI-Q in dementia group was significantly higher than that in control group (P<0.01). The incidence and severity of dementia in the elderly population in conclusion mental and behavioral symptoms were significantly higher than that of normal cognitive function, correct understanding and treatment of these symptoms is helpful to improve the quality of life of patients with senile dementia.
Key words: aged, over 80 years old; dementia; cognitive disorder; mental and behavioral symptoms
CLC number: R741.041 document code: A article number: 1006-2963 (2017)
Clinical analysis of behavioral and psychological symptoms of dementia in the oldest old with cognitive impairmentSHANG Yanchang*, WANG Shuhui*, GUO Yane, GUO Yanjun, ZHOU Bo, XIE Hengge, JIA Jianjun, WANG Zhenfu, WU Weiping#.#Department of Geriatric Neurology Chinese People s Liberation Army General Hospital ", Beijing 100853
* These authors equally to these contributed works
Corresponding author:WU Weiping,
ABSTRACT:Objective To study the prevalence and severity of behavioral and psychological symptoms of dementia (BPSD) in the oldest old with cognitive impairment. Methods Cross-sectional analysis was conducted in the oldest old in the memory clinics and in-patients in our hospitals. BPSD were determined using the Neuropsychiatric Inventory-Questionnaire (NPI-Q) assessment tool. The prevalence and severity of BPSD were compared between the normal - cognition (control) group and the dementia group. Results Of the 535 participants, 159 had normal cognition and dementia at enrollment. The 376 had results of NPI-Q showed that the dementia patients 86.7% of and 72.3% of the cognitively normal ones had at least one BPSD symptom in the last month. The top three common and severe symptoms were apathy/indifference (59.8%), night-time behavior problems (47.3%), and irritability/lability (46.8%), among which apathy/indifference and irritability/lability were significantly higher in the dementia group than the control group (P<0.01).Compared with the control group, the total score of NPI-Q was significantly higher in demented patients (P<0.01 Conclusions BPSD were more). Common and severe among patients with dementia. Proper assessment and treatment of these symptoms are essential for improving life quality in the demented oldest old.
Key words: aged, 80 and over; dementia; cognition disorder; behavioral and psychological symptoms
With the progress of population aging, which is the level of global dementia incidence in China by 2010 all types of dementia patients has reached 9 million 190 thousand people, including Alzheimer's disease (AD) patients is about 5 million 690 thousand, has become a serious threat to people's lives and health of the important disease [1]. Behavioral and psychological symptoms of dementia (behavioral and psychological symptoms of dementia, BPSD) as a kind of important symptoms of dementia, seriously affect the life of patients with dementia, and increase the burden on caregivers, has attracted more and more attention. At present, there are few studies on BPSD in patients with Alzheimer's disease at home and abroad. The neuropsychiatric inventory Insider (neuropsychiatric Inventory-Questionnaire, version NPI-Q) as an important assessment of BPSD, relatively simple, reliable and has high reliability and validity, is widely used in clinical [2-3]. In this study, NPI-Q scale was used to evaluate the incidence and severity of BPSD in elderly patients with cognitive impairment, so as to provide evidence for the diagnosis and treatment of BPSD.
1 objects and methods
1.1 the research object by using cross-sectional study, included in the 2009-01 - 2014-12 of PLA General Hospital and Beijing Friendship Hospital of Capital Medical University hospitalized elderly neurology neurology and memory clinic were older than 80 years with memory complaints of the old man a total of 535 cases, the average age (85.99 + 3.74) years old. All patients were screened by standard cognitive function, including the history of acquisition, neurological and physical examination, neuropsychological scale measurement, laboratory routine hematology and cranial imaging examination. The history of the patients included the names, gender, age, occupation, education level and other general demography